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But the high rates of side effects and discontinuations raise questions about the competitiveness of the therapy

Diabetes, Obesity & Metabolism, 25 (4), 961964

Compared to placebo, after 48 weeks of treatment with liraglutide 1.8 mg daily, the treatment group showed significant histological improvement [risk ratio = 4.3, 95% confidence interval (CI) = 1.017.7], including resolution of MASH and absence of liver fibrosis progression

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Other loci, such as glucokinase regulator (GCKR) and membrane bound O-acyltransferase domain-containing 7 (MBOAT7), influence glucose metabolism, phospholipid remodeling, and insulin sensitivity, highlighting the tight link between metabolic dysfunction and liver injury