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7 Maridebart cafraglutides peptideantibody conjugate design confers a long pharmacokinetic half-life, allowing for monthly dosing, which may significantly improve treatment adherence and convenience compared with weekly injectable regimens
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IV drips deliver vitamins and fluids and can have more immediate effects on hydration and energy
Due to the high expression profile of GLP-1R in pancreatic -cells, GLP-1 analogs (such as exendin-4) have been modified by different methods (to prolong half-life, maintain receptor binding affinity and reduce renal drug accumulation) for theranostic purposes and serve as excellent templates for future cardiovascular drug development[178-184]
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