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To investigate the difference in proportion of senescent fibroblasts between in keloids and normal skins

Available online at: (Accessed June 17, 2025)

Cureus 16 , e59319 (2024)

In astudyinvolving rats, BPC-157 was administered in doses of 0, 0.1, 0.25, and 0.5 micrograms/mL over 24 hours. Results showed that the 0.5 microgram/mL dose significantly increased growth hormone expression from day 1 to day 3, while lower doses also had similar effects. The study concluded that BPC-157 supplementation led to increased up-regulation of growth hormone in a dose and time-dependent manner

Results show in days. Metabolic adaptation takes weeks