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Full-text article Awosemo O, Neelakantan H, Watowich S, et al
Accordingly, it has issued new advice to check vitamin B12 serum levels in patients being treated with metformin who have symptoms suggestive of vitamin B12 deficiency.[] The proposed mechanisms to explain metformin-induced vitamin B12 deficiency among patients with T2DM include alterations in small bowel motility, which stimulates bacterial overgrowth and consequential vitamin B12 deficiency, competitive inhibition or inactivation of vitamin B12 absorption, alterations in IF levels, and interaction with the cubulin endocytic receptor
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People and mice differ in metabolism, body size, route exposure, and disease biology, so animal results cannot predict a person's outcome
Common Signs of Low B12 Not sure whether a shot makes sense
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