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Treatment reinitiation Among those who discontinued a GLP-1 receptor agonist, the cumulative incidence of reinitiating treatment was 41.1% (95% CI 40.5, 41.7) at 1 year and 57.4% (95% CI 56.7, 58.1) at 3 years when using a grace period of 90 days in the definition of treatment discontinuation (Fig

By designing the controls in from the start, because no amount of downstream analysis rescues an experiment that lacks them

Research published in Obesity (2023) found that patients discontinuing GLP-1 agonists without tapering regained 3050% of lost weight within 6 months

Arch Neurol 69:836841 Hardan AY, Fung LK, Libove RA, Obukhanych TV, Nair S, Herzenberg LA, Frazier TW, Tirouvanziam R (2012) A randomized controlled pilot trial of oral N-acetylcysteine in children with autism

Same goal, different roads getting there

The active ingredient is measured using calibrated compounding scales to ensure dosing accuracy