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Acknowledgements This work was supported by the Intramural Research Program of the NIH/National Institute of Environmental Health Sciences 1Z01ES090079

In vitro studies on aged human lymphocytes found that Epitalon reversed this heterochromatinization, increasing chromatin plasticity and making DNA more accessible to transcription factors

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MTB, AST and FPB performed the immunohistochemistry and FPB and ABM-B performed western blots