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The post frames week one as metabolic adjustment, not meaningful fat loss

doi: 10.1517/13543784.2011.630660 13 GLP-1 receptor agonists in the treatment of type 2 diabetes - state-of-the-art - PubMed

Excessive or sustained endoplasmic reticulum stress: one of the culprits of adipocyte dysfunction in obesity

Whether patients progress in diabetic retinopathy or not, I would rather we potentially ameliorate their macrovascular risk of cardiovascular and cerebrovascular diseases, instead of worrying about microvascular, eye-related risks that we can manage appropriately with current modalities. New Indication, New Patients