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Effective depletion of regulatory T cells allows the recruitment of mesothelin-specific cd8+ T cells to the antitumor immune response against a mesothelin-expressing mouse pancreatic adenocarcinoma
& Frhlich, L
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Within clinical trials conducted in the UK, the handling of IMPs including storage temperature requirements is overseen by the trial sponsor, the site pharmacist, and the relevant ethics and regulatory bodies
A secondary finding of notable metabolic significance: at week 72, 95% of participants with prediabetes at baseline in the tirzepatide groups returned to normoglycemia
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