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The Journal of Nutrition, 127 (9), 17761781

The practical rule: Refrigerate at 2 to 8 degrees C, minimize air exposure by keeping caps tightly sealed, and avoid products stored or shipped at room temperature for extended periods

Taking a proton pump inhibitor or other medications that reduce stomach acid for reflux or ulcers, as well as taking metformin for diabetes, can reduce absorption of B12 in food or supplements

Experimental investigations have reported increased expression of angiogenic mediators and enhanced vascularization in various laboratory models

Bridging that translational gulf demands a sharper focus on three interlocking realities: cost-effectiveness, real-world scalability, and sustained patient adherence

The theoretical concern most often raised relates to BPC-157s angiogenic properties