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hGLP-1, pGLP-1, eGLP-1 and Ex-4 (7 M) were incubated with purified human serum in 37 C incubator in the presence/absence of 100 M of DPP-4 inhibitor P32/98 (Santa Cruz Biotech), and aliquots of the reaction solutions were extracted after 0, 3, 6, 9 and 11 h incubation respectively, when TFA (0.1%) was added to terminate the reactions

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For patients with persistent reflux symptoms despite 8 weeks of PPI therapy or those with alarm features, referral to gastroenterology for upper endoscopy may be warranted, consistent with American College of Gastroenterology guidelines

Constipation: Also commonly reported

Acid Neutralizer : Bacteria in your mouth produce acids as they feed on sugars