This finding raised hopes that semaglutide could also benefit individuals with CKD who do not have diabetes
This particular trial is ongoing and will have additional follow-up that will focus on cirrhosis-free survival
LY3437943 (Retatrutide): discovery to clinical proof of concept (triple GLP-1/GIP/glucagon agonist, preclinical mechanism) Nature Reviews Endocrinology (2024) Multi-receptor agonists for metabolic disease (mechanism of GLP-1/GIP/glucagon co-activation) Diabetes Care (2024) Incretin-based therapies: GLP-1, GIP, and glucagon receptor pharmacology (metabolic pathways, energy expenditure) NEJM (2023) Supplementary Material Jastreboff et al
Your weight-loss goals and how your body has responded to treatments before
If fatigue persists or worsens over time, checking B12 levels, thyroid function, and other nutritional markers is warranted
proper storage is the other half