Common side effects include nausea, vomiting, and diarrhea, which usually decrease over time
This dual mechanism is why tirzepatide is widely considered a breakthrough in the GLP-1 drug class
The main consideration is ensuring adequate hydration and electrolytes, as fasting plus peptide use may increase demands on both
Although the drug has been promoted as safe and effective, with few long-term side effects, Ozempic has been linked to severe gastrointestinal issues, such as stomach paralysis (gastroparesis), ileus, abdominal obstructions and other adverse effects
Since these are not necessarily visible they can be frustrating, however these are the building blocks to long-term success and ensuring that GLP-1 supplementation is working
And the frustrating part is that degraded semaglutide often looks identical to fresh semaglutide, so you cannot rely on visual inspection alone to determine safety