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injected with 1.5 10 11 genome copies per mouse of AAV8.TBG.pi.egfp.wpre.bgh (AAV-GFP

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In 1973, John Brown discovered the glucose-dependent insulinotropic polypeptide (GIP) employing peptide purification and protein sequencing, it was shown to have an incretin effect, increasing Insulin release triggered by glucose intake after oral administration [11]

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