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Neurological changes A lack of vitamin B12 can cause neurological problems, which affect your nervous system, such as: vision problems memory loss pins and needles loss of physical co-ordination (ataxia), which can affect your whole body and cause difficulty speaking or walking damage to parts of the nervous system (peripheral neuropathy), particularly in the legs If neurological problems do develop, they can sometimes be irreversible
For patients who have concerns with any deficiencies or low vitamin B12 we advise them to call their primary care provider
Overall, the three-dimensional structure of hGS resembles that of the eukaryotic GS (Polekhina et al., 1999
Activated microglia release even more neurotoxic mediators, perpetuating a state of chronic neuroinflammation
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Juskowa et al
