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Thiazolidinedione Use and the Longitudinal Risk of Fractures in Patients With Type 2 Diabetes Mellitus

Metformin is thought to exert these powerful effects primarily by counteracting insulin resistance to curtail hepatic glucose output and increase insulin-stimulated glucose uptake in muscle and fat [3]

Semaglutide is typically initiated at a low dose and is gradually increased over time

According to available data, it is most commonly observed in Caucasians and Scandinavians, while Asian and African populations are less affected (196)

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