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Age-dependence of hypertensivenormotensive differences in plasma norepinephrine
My concern is that such high levels may have subtle toxic effects
A 2021 study showed liposomal glutathione achieved 14-20% reduction in oxidized/reduced GSH ratio
Topical effects Most reported topical effects are mild and local: redness, tingling, dryness, or transient irritation at the application site, typically more common with concentrations above 4%
Glutathione levels also are lower and oxidative stress is higher in conditions associated with mitochondrial dysfunction, including ageing, HIV infection, diabetes, neurodegenerative disorders, cardiovascular disorders, neurometabolic diseases, cancer, obesity and other conditions
This reduction in GSH synthesis may contribute to excessive oxidative stress in infants
