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doi: 10.3389/fendo.2021.721198 101

In this 72-week trial TZP 10 mg and 15 mg determinate a clinically meaningful reduction in BW, with a safety profile comparable to GLP1-RA- based therapies (104)

If cramps are severe, persistent beyond 4-6 weeks of electrolyte correction, or associated with visible muscle swelling, a creatine kinase (CK) level is warranted to rule out rhabdomyolysis, statin-induced myopathy, or other myopathic processes

According to the Global Burden of Disease Study, both type 1 and type 2 diabetes mellitus substantially contribute to chronic kidney disease (CKD)-related disability-adjusted life-years (DALYs)

(84) highlighted the neuroprotective potential of GLP-1 RAs, particularly in reducing protein aggregation and improving mitochondrial function

When it diminishes rapidly, the skin loses that support, causing it to appear loose and deflated