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For B12 to be absorbed, it requires a protein called intrinsic factor (IF), which is secreted by the stomachs parietal cells (3)

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Regulation of adipogenesis by lymphatic fluid stasis: part II

doi: 10.1016/j.cmet.2017.09.021, 91

As a class, however, these agents work similarly where they mimic the structure of GLP-1 in vivo , and thus, can bind the GLP-1R, but are not subject to degradation by DPP-4