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Semaglutide is highly effective for obesity management, achieving mean weight losses of 1517% in clinical trials
Rovamo LM, Salmenpera L, Arjomaa P, et al
While its efficacy and safety profile are comparable to oral Wegovy , it falls significantly short of Eli Lillys subcutaneous tirzepatide the gold standard of GLP-1 analogs to date (technically a dual agonist mimicking both GLP-1 and GIP)
The most commonly reported side effects for both agents are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation
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