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By mimicking the action of the naturally occurring GLP-1 hormone, semaglutide works to enhance insulin secretion in response to meals, decrease glucagon release, and slow gastric emptying, all of which contribute to better blood sugar management

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A p value of less than 0.05 was considered significant

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Conclusions At the end of 12 months of follow-up, patients with obesity or overweight with ORCs treated with semaglutide 2.4 mg had a significantly greater reduction in absolute and percentage change in body weight, as well as improvements in cardiometabolic risk factors compared with patients not treated with OM

doi:10.1017/S0029665107005563 Hedin C, Whelan K, Lindsay JO