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Case reports and small clinical series suggest that GLP-1 initiation may improve pain severity, reduce swelling, and enhance mobility in select lipedema patients

The BNF advises that patients presenting with neurological symptoms should receive 1000 mcg i.m

Stress and cortisol Chronic stress elevates cortisol, and high cortisol does more than make you feel on edge: It encourages fat storage, particularly around the abdomen where visceral fat accumulates

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Furthermore, the literature indicates that aside from their benefits in weight management and glycemic control, GLP-1 RAs have favorable effects on metabolic profiles, including blood pressure and lipid levels 22

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