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In a previous study, we reported that maternal age and number of pregnancies increased lipid peroxidation (TBARS) in breast milk due to the increase in metabolism and the consequent production of ROS (9)

One example mentioned: the drug Tirzepatide (brand name Mounjaro for diabetes, Zepbound for weight loss) activates both GLP1 and GIP pathways

showed that depletion in glutathione levels due to oxidative stress is related to microglial glutamate release [14]

doi: 10.1093/humrep/deq044 16

275,276,277 The insulin-like growth factor 1 (IGF-1)-AKT-mTOR pathway responds to nutrient availability and mitogens through signaling related to cell division and death