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Hanafy, B

showed that the L-Ala diastereomer was nearly 100-fold less potent than GLP-1 itself in terms of stimulating insulin release from isolated rat pancreases, while the D-Ala diastereomer matched GLP-1 in potency

Studies suggest this derivative may address both extrinsic photoaging and intrinsic hyperpigmentation without the formulation challenges of parent compound ascorbic acid

Leah Joseph, MD, FACP

The primary reason is that the glucose-lowering action of metformin, when used alone, is at least as effective as that of any other oral glucose-lowering drug, without promoting weight gain and only rarely causing excessively low blood sugar

Regulatory Considerations for Peptide Research In Canada, injectable peptides are regulated as prescription drugs