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Neurons pretreated with Dihexa demonstrate significantly enhanced survival when exposed to reactive oxygen species, excitotoxic glutamate concentrations, or metabolic impairment compared to untreated controls
The maintenance week allows metabolic rate to recover somewhat while preventing regain if calories are carefully controlled
One employer in Nomi Health's data found GLP-1 users had 40% lower medical costs despite 2.5x higher pharmacy spend, with fewer prescriptions for comorbidities and better health markers overall
Despite good discriminative performance, the complexity of these models may limit their practicality in clinical practice
Dulaglutide has no role in obesity-first prescribing under current guidelines
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