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Injectable GLP-1s have the strongest evidence for significant, sustained weight loss.For patients who prioritize needle-free treatment or struggle with adherence to strict oral dosing requirements, ODT formulations may be a practical alternative when used under close medical supervision
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This is not a moment to replicate past LoE playbooks, its a moment to redefine them
Stop-and-switch decisions should be made with a clinician, especially when other glucose-lowering medicines are involved
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