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6770 Additional studies are warranted to investigate whether the potential anti-inflammatory effects of GLP-1 receptor agonism may in fact play a role in the potential kidney-protective benefit of the GLP-1 RA drug class or certain of the specific compounds

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Oxidative damage to proteins involved in the acrosome reaction, such as acrosin and hyaluronidase, impairs the sperms ability to release these enzymes, preventing successful penetration of the oocyte (79, 80)

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