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Key mechanisms of GLP-1 medications: Enhanced insulin secretion in response to meals Reduced appetite through central nervous system effects Delayed gastric emptying, promoting satiety Improved glycaemic control in people with diabetes Have questions about Wegovy

a Calculated by mutating Aib to Ala and Igl to Phe, respectively, in Semaglutide and SR18

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blue arrows), and the apo-GLP-1R (obtained by removing both the G s protein and GLP-1

Patients included in our treatment cohort were required to have a minimum of 12 months of continuous duration of GLP-1 prescriptions in order to limit the treatment sample to those who were most likely to continue care