severe or persistent upper abdominal pain should prompt urgent medical assessment [10] [11] Dehydration and acute kidney injury (AKI): gastrointestinal fluid losses can lead to dehydration, which may precipitate AKI, particularly in those with pre-existing renal impairment or those taking nephrotoxic medicines Delayed gastric emptying: this may affect the absorption of orally administered medicines, including contraceptive pills and thyroid replacement therapy [11] Injection site reactions: redness, bruising, or discomfort at the subcutaneous injection site Heart rate changes: increases in resting heart rate have been noted with GLP-1 class agents [14] [15] Hypoglycaemia: particularly if used alongside insulin or sulphonylureas Potential pancreatitis risk: a class concern with GLP-1 receptor agonists
doi: 10.18632/oncotarget.6868 35 PastorekovaSGilliesRJ
Gestational Diabetes : Associated with autoimmune condition where destruction of beta cells of pancreas take place and this is a partial insulin dependent diabetes
Sinha DK, et al
Persistent nausea and vomiting that prevents you from keeping down food, fluids, or other essential medications
Two Phase 3 clinical trials, RECONNECT 1 and RECONNECT 2, enrolled more than 1,200 premenopausal women and demonstrated its effectiveness