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Individuals with T2DM taking tirzepatide, a dual GIP and GLP- 1 receptor agonist, experienced better weight loss and blood sugar control than patients taking GLP- 1 receptor agonism
However, in an in vitro simulation of GI digestion, inulinase has been shown to effectively break down high-fructan ingredients, including inulin and garlic, as well as a high-fructan test meal containing garlic, onion, Brussels sprouts, and black beans.28 In addition, preliminary in-house randomized, blinded, placebo-controlled trials conducted by Kiwi Biosciences demonstrated significantly reduced flatulence and diarrhea events in healthy individuals who were given supplemental fructan hydrolase powder with a highly concentrated source of fructan in chicory root bars.26 More research is needed to determine whether inulinase and fructan hydrolase are effective tools for symptom management in IBS
On May 2, 2026, The Lancet published a randomized, double-blind, placebo-controlled trial (Klausen et al., Copenhagen University Hospital) testing once-weekly semaglutide 2.4 mg in 108 treatment-seeking adults with moderate to severe alcohol use disorder and comorbid obesity
The deal marks a noteworthy development for Ro, which has been one of the major telehealth platforms providing compounded copies of GLP-1 obesity drugs during shortages of the branded treatments
It stimulates dermal papilla cell proliferation and protects these cells from noxious stimuli including dihydrotestosterone (DHT)-induced stress, the primary driver of androgenic alopecia
