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Mechanistically, SELENOP promotes IR by inhibiting the phosphorylation of Acetyl-CoA carboxylase (ACC), a critical enzyme in lipid metabolism

Indeed, the SURPASS-CVOT study, which compares tirzepatide head-to-head with dulaglutide, will likely provide more comprehensive answers (expected by the end of 2024)

Proper injection technique includes maintaining 2.55 cm distance between consecutive injections and avoiding scars, moles, or areas with skin abnormalities

The color variation does not impact potency, purity, or effectiveness

Diabetes Care 2019;42:S90-S102

In the REDEFINE 1 trial, CagriSema produced 20.4% body weight loss over 68 weeks