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That is important, because it confirms that VEGFR2 is not just one of many mechanisms, but truly a causal pathway

The Imerslund-Grasbeck syndrome is a rare autosomal recessive condition characterized by both a specific congenital deficiency in cobalamin absorption and proteinuria (248)

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- Digoxin, methotrexate, cyclosporine: because it can increase the toxicity of these drugs through their effects on renal prostaglandins

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