AstraZenecas GLP-1 pill, elecoglipron, which in phase II trials showed clinically meaningful weight loss of up to 10.5% at 26 weeks and 11.8% at 36 weeks in the highest-dose groups of adults without diabetes 21
In uveitis, chronic ocular inflammation elevates cytokine (IL-6, TGF) and matrix metalloproteinase (MMP-2 and MMP-9) levels, which collectively degrade the capsular basement membrane, stimulate LEC proliferation, and promote EMT (134138)
The VITAstir clinic has made this a very smooth process
Subsequent analyses were performed using residual plasma samples from 19 of these 20 subjects
Given the strength of these preliminary signals, the field must now shift focus toward conducting well-powered phase 3 RCTs to validate these associations
Initially, a low dose is always a recommendation with any drug you take