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Inverse agonists reverse constitutive receptor activity, thereby decreasing signalling below basal levels

These GLP-1 agonists have skyrocketed in popularity

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The goal is to lose fat, preserve muscle, and improve long-term movement, living, and functioning

Understanding this timeline helps set realistic expectations and prevents unnecessary worry during early treatment

Throughout the trial, researchers will track changes in participants' drinking habits, overall physical health and quality of life to assess whether the medication could eventually become a viable new treatment option for alcohol use disorder