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Shaking will denature the peptide

This twice daily injection established the drug class in clinical practice as adjunct therapy for adults not adequately controlled on oral agents

Lilly also reported diarrhea in 18.7%, 26.3%, and 22.8%, and vomiting in 15.7%, 15.0%, and 17.6% across the same retatrutide dose groups [9]

Starting dose considerations