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Brunner argued that most bills under consideration throughout the country dont do anything to improve patient safety. But he said he supports Indianas amended bill because it aligns the state with others that have set standards to hold compound pharmacies accountable to the Food, Drug and Cosmetic Act

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These include:[ref] Inflammatory cytokines (IL-1B, IL-33), which cause the release of IL-6, TNF, IL-8, and VEGF Heavy metals (aluminum, cadmium, mercury) Herbicides (atrazine, glyphosate) Pathogens (Lyme disease, lipopolysaccharides from bacteria, certain viruses, and mold spores) These triggers can cause a two-phase reaction : Immediately released mediators include histamine, TNF, tryptase, RANKL, and serotonin

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