GLP-1 was discovered when, while studying the incretin effect, scientists noticed certain gut hormones spurred insulin release after meals
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Liraglutide 3.0 mg for weight management: a population pharmacokinetic analysis
Successfully losing weight can be very difficult and often leads to unhealthy or unsafe habits, which is why medical weight-loss programs were created
Chia YC, Ching SM, Ooi PB, Beh HC, Chew MT, Chung FFL, et al
Despite this, it was removed from the market in the late 1970s because of its high risk of lactic acidosis (Luft et al., 1978)