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95% CI, 0.891.17), it was shown to be non-inferior to placebo in terms of cardiovascular safety ( The first study to demonstrate superiority over placebo was the LEADER study, in which 9,340 patients were assigned to either liraglutide or placebo

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Flow of patients through the trial Perkovic et al , NEJM 2024 The randomized participants had a mean age of 66.6 years