References Lee YS, Jun HS
19,19 (37.54 ) 23,99 (46.92 )
The authors reported a 55.8% reduction in facial wrinkle volume and a 32.8% reduction in wrinkle depth compared with control serum, alongside in vitro evidence that GHK-Cu increased both collagen and elastin production in human dermal fibroblasts at concentrations as low as 0.01 nM [4]
Although mechanisms of bisphenol A action are probably diverse, it should be underlined with respect to the topic of the present review that this EDC increases the generation of hydrogen peroxide (H 2 O 2 ), being one of the basal forms of ROS, in vitro and in vivo models (via increasing DUOX2 [the enzyme responsible for H 2 O 2 generation in the thyroid] mRNA level) and decreases iodine uptake (reduces NIS mRNA level) and TPO activity [45]
Its primary function is to mimic the action of the bodys natural growth hormone-releasing hormone (GHRH) , stimulating the pituitary gland to produce and release growth hormone (GH)
Performance optimization Improving energy production and recovery capacity