Suppresses glucagon secretion: GLP-1 suppresses glucagon secretion and decreases hunger
DRUG INTERACTIONS As with other medications, topiramate can interact with alcohol, marijuana and certain medications, including antiepileptic drugs, CNS depressants, oral contraceptives, lithium, other carbonic anhydrase inhibitors, hydrochlorothiazide, pioglitazone and amitriptyline
It also reduces appetite by slowing down the time it takes for the stomach to empty and interacting with areas in the brain harboring GLP-1 receptors to signal satiety
Wang X, Liu M, Chu Y, Liu Y, Cao X, Zhang H, et al
Pumping and discarding milk doesnt eliminate exposure risk because GLP-1 drugs stay in your system for days
Thyroid Tumors: Animal studies suggest a potential risk for certain thyroid tumors, though the relevance to humans is still under investigation