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That is a clinically meaningful secondary benefit for patients with type 2 diabetes, but it is not the same as the weight loss observed in obesity-specific trials at higher doses

Rare neuro-ophthalmic events such as ophthalmic migraine warrant monitoring despite low incidence 64

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In clinical practice, GLP-1 RAs are primarily employed to stabilize blood glucose levels in patients with diabetes, with established efficacy

Notably, persistent or new users of GLP-1 RAs exhibited better survival and kidney outcomes compared to ever users, with persistent users also showing superior MACEs and MAKEs outcomes

10.1210/en.2011-1795 26 DavidsonJ