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Gene therapy studies using HGF have demonstrated beneficial effects in animal models of amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and cerebral ischemia, with HGF treatment promoting neurite extension, increasing synaptogenesis, and enhancing functional recovery
New England Journal of Medicine , 385 (6), 503515
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The term "reduced" refers to the chemical state of the molecule
It would require somebody to use the agent continuously, and on top of that, the psychoactive effects during that time would preclude the use, especially in the guise that there are other agents that don't have these psychoactive effects or last longer and lower IOP better
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