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IGF-1 is necessary for MSC differentiation, not recruitment during bone remodeling To examine the mechanism of the reduced bone mass in the MSC- Igf1r / mice, we performed immunohistochemical staining for Osterix and Osteocalcin to label osteoprogenitors and mature osteoblasts, respectively in mouse femora
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Understanding these mechanisms is crucial for developing effective strategies to combat drug resistance
evaluated the association between serum UA levels, cerebrospinal fluid biomarkers of AD, and longitudinal cognitive decline using the Alzheimers Disease Neuroimaging Initiative database ( n = 1064, including 271 healthy subjects, 596 MCI, and 197 AD)
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