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By constantly signaling to the brain that the body is full, peristalsis (rippling GI waves that push contents through the gut) is slowed, thereby disrupting the bodys natural digestion process. According to Fereday: The anecdotes of the early adopters are not necessarily that representative of how things will play out if this class of drugs goes mainstream

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Together, these factors played a major role in the results seen in studies, making lifestyle habits one of the biggest drivers of progress alongside medication

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