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On GLP-1, there is real human evidence: in a trial in people with metabolic syndrome, pasteurized Akkermansia muciniphila increased GLP-1 (Suenaert et al., 2026)
W., Rosenkilde, M
A 2025 study of 141 people with BED found that 70.2 percent of people treated with a combination of therapy and Vyvanse went into remission, making it almost twice as effective as medication or therapy alone
Note: Eli Lilly terminated a Phase IIb trial combining bimagrumab with tirzepatide (Zepbound) for "strategic business reasons," though a separate non-diabetic obesity trial remains ongoing
Weight loss drugs are not invasive, but they have side effects
Most patients are comfortable with self-injection after the first time
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