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This contrasts with controlled animal model findings, which may not accurately reflect real-world complexities

DOI: 10.1186/s12903-019-0841-2

8,9 Table 1 Risk Factors for Vitamin B12 Deficiency A multicenter randomized controlled trial of 390 patients with diabetes mellitus showed that those taking 850 mg of metformin three times per day had an increased risk of vitamin B 12 deficiency (number needed to harm = 14 per 4.3 years) and low vitamin B 12 levels (number needed to harm = 9 per 4.3 years) vs

Typically, those who are willing to do more daily at-home maintenance (Lasercap, medications, supplements) can avoid having injections as frequently

Dietary Adjustments Vitamin B12-rich foods: Eggs, dairy products, poultry, fish, and fortified cereals

removing vials from the carton and storing them on an open shelf under fluorescent or natural light is a documented degradation accelerant