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Similarly, elevated global DNA methylation, Dnmt activity, and 5-methylcytosine but decreased Tet activity and 5-hydroxymethylcytosine were observed in the GSH-deficient hepatocytes and the liver of HFD-fed mice

Under cystine-restricted conditions, SCD erythroblasts showed significantly increased ROS and ferroptosis signals by 2,7-dichlorofluorescein (DCF) and Bodipy-C11 staining (Fig

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