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Go to urgent care or an emergency department if: abdominal pain is severe or localized to the right upper quadrant, you develop fever above 38.5C with GI symptoms, you notice yellowing of the skin or eyes, urine turns dark brown with pale stools, or heart rate exceeds 110 at rest without other explanation

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Quantitative analysis of caspase-3 relative to -actin (Figure 7D) and the Bax/Bcl-2 ratio (Figure 7E) confirmed these observations, indicating a substantial reduction in apoptotic markers and an increase in anti-apoptotic markers in the GO@GSH-FA treatment group

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This result is independent of the proliferative effects of EGFR on -cell function, which suggests an integral role for EGFR in the coordination of insulin secretion

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