glp 1 death GLP-1 receptor agonist use was associated with a lower risk of in cancer patients with brain metastases and type 2 diabetes, a retrospective cohort study found. https://www.medpagetoday.com/hematologyoncology/braincancer/120261 glp-1 receptor agonist use and

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doi:10.2147/ijn.S34396

Longer-term use (6+ months) may create more durable improvements where enhanced dermal architecture supports ongoing collagen synthesis at rates intermediate between treatment peaks and pre-treatment baseline, potentially maintaining 40-60% of peak improvements indefinitely without continuous peptide application

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Chronically increasing IGF-1 also raises questions that require long-term safety data rather than an assumption that a higher level is necessarily beneficial