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Oral B12 supplements rely on a complex absorption pathway in the gut involving a protein called intrinsic factor

When you're deficient, the symptoms are usually gradual: fatigue, brain fog, low mood, tingling in hands or feet, unexplained weakness

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however, evidence from studies that performed post-intervention follow-ups found fibromyalgia impact improved over time in those who had received PNE

Many conditions cause similar symptoms, and inappropriate supplementation may mask underlying diagnoses whilst providing no benefit