Dihexa-mediated protection is attenuated by co-treatment with the HGF antagonist 6-AH, further evidence that HGF activation is a component of the observed protection
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Regulating Satiety Pathways: In the hypothalamus, GLP-1 RAs stimulate neurons that promote satiety (POMC/CART neurons) and inhibit neurons that drive hunger (NPY/AgRP neurons), reducing food intake and enhancing fullness (Zheng et al., 2024)
doi:10.1007/s00380-004-0822-4
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In addition, preventive approaches to diabetic cataracts include AR inhibitors, glycation inhibitors, and antioxidants, but none of these drugs has yet been formulated to offer a fundamental treatment 58,59,60